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Generation of two induced pluripotent stem cell lines carrying the phospholamban R14del mutation for modeling ARVD/C

The phospholamban (PLN) R14del mutation is associated with arrhythmogenic right ventricular dysplasia (ARVD/C). ARVD/C is a cardiac disease characterized by arrhythmias and structural abnormalities in the right ventricle. Because PLN is a regulator of calcium release, this mutation can have deleteri...

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Detalles Bibliográficos
Autores principales: Vera, Carlos D., Manhas, Amit, Shenoy, Sushma P., Wheeler, Matthew T., Sallam, Karim, Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476586/
https://www.ncbi.nlm.nih.gov/pubmed/35700631
http://dx.doi.org/10.1016/j.scr.2022.102834