Impact of cytochrome P450 2D6 polymorphisms on decision-making and clinical outcomes in adjuvant hormonal therapy for breast cancer

BACKGROUND: There are concerns that tamoxifen is less effective in Asian women because of the high prevalence of impaired function cytochrome P450 2D6 (CYP2D6) polymor-phisms. AIM: To evaluate how knowledge of CYP2D6 genotype impacted the choice of hormonal agent and how CYP2D6 genotype and agent we...

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Detalles Bibliográficos
Autores principales: Tan, Ern-Yu, Bharwani, Lavina, Chia, Yee-Hong, Soong, Richie C T, Lee, Sherylyn S Y, Chen, Juliana J C, Chan, Patrick M Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Prospective Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476606/
https://www.ncbi.nlm.nih.gov/pubmed/36160461
http://dx.doi.org/10.5306/wjco.v13.i8.712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476606/
https://www.ncbi.nlm.nih.gov/pubmed/36160461
http://dx.doi.org/10.5306/wjco.v13.i8.712

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