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Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays

Most epigenetic epidemiology to date has utilized microarrays to identify positions in the genome where variation in DNA methylation is associated with environmental exposures or disease. However, these profile less than 3% of DNA methylation sites in the human genome, potentially missing affected l...

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Detalles Bibliográficos
Autores principales: Flynn, Robert, Washer, Sam, Jeffries, Aaron R, Andrayas, Alexandria, Shireby, Gemma, Kumari, Meena, Schalkwyk, Leonard C, Mill, Jonathan, Hannon, Eilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476619/
https://www.ncbi.nlm.nih.gov/pubmed/35567415
http://dx.doi.org/10.1093/hmg/ddac112