RTL1/PEG11 imprinted in human and mouse brain mediates anxiety-like and social behaviors and regulates neuronal excitability in the locus coeruleus

RTL1/PEG11, which has been associated with anxiety disorders, is a retrotransposon-derived imprinted gene in the placenta. However, imprinting patterns and functions of RTL1 in the brain have not been well-investigated. We found Rtl1 was paternally, but not maternally, expressed in brain stem, thala...

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Detalles Bibliográficos
Autores principales: Chou, Ming-Yi, Hu, Meng-Chuen, Chen, Pin-Yu, Hsu, Chi-Lin, Lin, Ting-Yu, Tan, Mao-Jia, Lee, Chih-Yu, Kuo, Meng-Fai, Huang, Pei-Hsin, Wu, Vin-Cent, Yang, Shih-Hung, Fan, Pi-Chuan, Huang, Hsin-Yi, Akbarian, Schahram, Loo, Tsui-Han, Stewart, Colin L, Huang, Hsiang-Po, Gau, Susan Shur-Fen, Huang, Hsien-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476620/
https://www.ncbi.nlm.nih.gov/pubmed/35567414
http://dx.doi.org/10.1093/hmg/ddac110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476620/
https://www.ncbi.nlm.nih.gov/pubmed/35567414
http://dx.doi.org/10.1093/hmg/ddac110

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