Mice lacking MBNL1 and MBNL2 exhibit sudden cardiac death and molecular signatures recapitulating myotonic dystrophy

Myotonic dystrophy (DM) is caused by expansions of C(C)TG repeats in the non-coding regions of the DMPK and CNBP genes, and DM patients often suffer from sudden cardiac death due to lethal conduction block or arrhythmia. Specific molecular changes that underlie DM cardiac pathology have been linked...

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Detalles Bibliográficos
Autores principales: Lee, Kuang-Yung, Seah, Carol, Li, Ching, Chen, Yu-Fu, Chen, Chwen-Yu, Wu, Ching-I, Liao, Po-Cheng, Shyu, Yu-Chiau, Olafson, Hailey R, McKee, Kendra K, Wang, Eric T, Yeh, Chi-Hsiao, Wang, Chao-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476621/
https://www.ncbi.nlm.nih.gov/pubmed/35567413
http://dx.doi.org/10.1093/hmg/ddac108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476621/
https://www.ncbi.nlm.nih.gov/pubmed/35567413
http://dx.doi.org/10.1093/hmg/ddac108

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