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Developmental disruption to the cortical transcriptome and synaptosome in a model of SETD1A loss-of-function
Large-scale genomic studies of schizophrenia implicate genes involved in the epigenetic regulation of transcription by histone methylation and genes encoding components of the synapse. However, the interactions between these pathways in conferring risk to psychiatric illness are unknown. Loss-of-fun...
Autores principales: | Clifton, Nicholas E, Bosworth, Matthew L, Haan, Niels, Rees, Elliott, Holmans, Peter A, Wilkinson, Lawrence S, Isles, Anthony R, Collins, Mark O, Hall, Jeremy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476630/ https://www.ncbi.nlm.nih.gov/pubmed/35531971 http://dx.doi.org/10.1093/hmg/ddac105 |
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