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Gene mining and efficient biosynthesis of a fungal peptidyl alkaloid
OBJECTIVE: Peptidyl alkaloids, a series of important natural products can be assembled by fungal non-ribosomal peptide synthetases (NRPSs). However, many of the NRPSs associated gene clusters are silent under laboratory conditions, and the traditional chemical separation yields are low. In this stud...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476675/ https://www.ncbi.nlm.nih.gov/pubmed/36117764 http://dx.doi.org/10.1016/j.chmed.2020.11.003 |