Chrysophanol localizes in mitochondria to promote cell death through upregulation of mitochondrial cyclophilin D in HepG2 cells

OBJECTIVE: Chrysophanol (Chry) displays potent anticancer activity in human cancer cells and animal models, but the cellular targets of Chry have not been fully defined. Herein, we speculated whether mitochondria were a target involved in Chry-induced cytotoxicity. METHODS: Human liver cancer cell l...

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Detalles Bibliográficos
Autores principales: Xie, Yu, Zhang, Ling, Li, Yuan-yuan, He, Dian, Zheng, Li-fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476804/
https://www.ncbi.nlm.nih.gov/pubmed/36117497
http://dx.doi.org/10.1016/j.chmed.2020.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476804/
https://www.ncbi.nlm.nih.gov/pubmed/36117497
http://dx.doi.org/10.1016/j.chmed.2020.11.006

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