Sirolimus increases the anti-cancer effect of Huai Er by regulating hypoxia inducible factor-1α-mediated glycolysis in hepatocellular carcinoma

BACKGROUND: Glycolysis caused by hypoxia-induced abnormal activation of hypoxia inducible factor-1α (HIF-1α) in the immune microenvironment promotes the progression of hepatocellular carcinoma (HCC), leading to enhanced drug resistance in cancer cells. Therefore, altering the immunosuppressive micro...

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Detalles Bibliográficos
Autores principales: Zhou, Lin, Zhao, Yang, Pan, Li-Chao, Wang, Jing, Shi, Xian-Jie, Du, Guo-Sheng, He, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476881/
https://www.ncbi.nlm.nih.gov/pubmed/36157928
http://dx.doi.org/10.3748/wjg.v28.i32.4600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476881/
https://www.ncbi.nlm.nih.gov/pubmed/36157928
http://dx.doi.org/10.3748/wjg.v28.i32.4600

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