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Mechanistic Insights into Photodynamic Regulation of Adenosine 5′-Triphosphate-Binding Cassette Drug Transporters

[Image: see text] Efforts to overcome cancer multidrug resistance through inhibition of the adenosine triphosphate-binding cassette (ABC) drug transporters ABCB1 and ABCG2 have largely failed in the clinic. The challenges faced during the development of non-toxic modulators suggest a need for a conc...

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Detalles Bibliográficos
Autores principales: Liang, Barry J., Lusvarghi, Sabrina, Ambudkar, Suresh V., Huang, Huang-Chiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476936/
https://www.ncbi.nlm.nih.gov/pubmed/36118950
http://dx.doi.org/10.1021/acsptsci.1c00138