Dihydromyricetin Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting SPHK1/mTOR Signaling and Targeting Ferroptosis

BACKGROUND: Dihydromyricetin (DHM) exerts protective effects in various brain diseases. The aim of this research was to investigate the biological role of DHM in cerebral ischemia reperfusion (I/R) injury. METHODS: We generated a rat model of cerebral I/R injury by performing middle cerebral artery...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Jiangbo, Zhang, Tingting, Li, Peichun, Wang, Dong, Liu, Tao, Xu, Shunliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477154/
https://www.ncbi.nlm.nih.gov/pubmed/36118165
http://dx.doi.org/10.2147/DDDT.S378786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477154/
https://www.ncbi.nlm.nih.gov/pubmed/36118165
http://dx.doi.org/10.2147/DDDT.S378786

Ejemplares similares