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Dihydromyricetin Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting SPHK1/mTOR Signaling and Targeting Ferroptosis

BACKGROUND: Dihydromyricetin (DHM) exerts protective effects in various brain diseases. The aim of this research was to investigate the biological role of DHM in cerebral ischemia reperfusion (I/R) injury. METHODS: We generated a rat model of cerebral I/R injury by performing middle cerebral artery...

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Detalles Bibliográficos
Autores principales:	Xie, Jiangbo, Zhang, Tingting, Li, Peichun, Wang, Dong, Liu, Tao, Xu, Shunliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477154/ https://www.ncbi.nlm.nih.gov/pubmed/36118165 http://dx.doi.org/10.2147/DDDT.S378786

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