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NMR study of human macroPARPs domains: (1)H, (15)N and (13)C resonance assignment of hPARP14 macro domain 2 in the free and the ADPr bound state

hPARP14 is a human ADP-ribosyl-transferase (ART) that belongs to the macroPARPs family, together with hPARP9 and hPARP15. It contains a tandem of three macro domains (MD) while each of them has different properties. The first one, namely MD1, has not been reported to exhibit a high binding affinity...

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Detalles Bibliográficos
Autores principales: Fourkiotis, Nikolaos K., Charalampous, Periklis, Tsika, Aikaterini C., Kravvariti, Konstantina P., Sideras-Bisdekis, Christos, Gallo, Angelo, Spyroulias, Georgios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477163/
https://www.ncbi.nlm.nih.gov/pubmed/36107366
http://dx.doi.org/10.1007/s12104-022-10110-6