SHP2 inhibition improves celastrol-induced growth suppression of colorectal cancer

This study aimed to explore novel targets for celastrol sensitization in colorectal cancer (CRC) based on differentially regulated signals in response to high- or low-dose celastrol. Targeting signals were investigated using Western blotting or phosphorylated receptor tyrosine kinase (RTK) arrays. C...

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Detalles Bibliográficos
Autores principales: Zhang, Linxi, Hu, Xuefei, Meng, Qingying, Li, Ye, Shen, Hao, Fu, Yating, Zhang, Fan, Chen, Jiahui, Zhang, Wei, Chang, Wenjun, Pan, Yamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477229/
https://www.ncbi.nlm.nih.gov/pubmed/36120370
http://dx.doi.org/10.3389/fphar.2022.929087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477229/
https://www.ncbi.nlm.nih.gov/pubmed/36120370
http://dx.doi.org/10.3389/fphar.2022.929087

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