Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917

Enteric microbial pathogens, including Escherichia coli, Shigella and Cryptosporidium species, take a particularly heavy toll in low-income countries and are highly associated with infant mortality. We describe here a means to display anti-infective agents on the surface of a probiotic bacterium. Be...

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Detalles Bibliográficos
Autores principales: Gelfat, Ilia, Aqeel, Yousuf, Tremblay, Jacqueline M., Jaskiewicz, Justyna J., Shrestha, Anishma, Lee, James N., Hu, Shenglan, Qian, Xi, Magoun, Loranne, Sheoran, Abhineet, Bedenice, Daniela, Giem, Colter, Manjula-Basavanna, Avinash, Pulsifer, Amanda R., Tu, Hann X., Li, Xiaoli, Minus, Marilyn L., Osburne, Marcia S., Tzipori, Saul, Shoemaker, Charles B., Leong, John M., Joshi, Neel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477280/
https://www.ncbi.nlm.nih.gov/pubmed/36107831
http://dx.doi.org/10.1371/journal.ppat.1010713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477280/
https://www.ncbi.nlm.nih.gov/pubmed/36107831
http://dx.doi.org/10.1371/journal.ppat.1010713

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