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Identification of quantitative trait loci for survival in the mutant dynactin p150Glued mouse model of motor neuron disease
Amyotrophic lateral sclerosis (ALS) is the most common degenerative motor neuron disorder. Although most cases of ALS are sporadic, 5–10% of cases are familial, with mutations associated with over 40 genes. There is variation of ALS symptoms within families carrying the same mutation; the disease ma...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477371/ https://www.ncbi.nlm.nih.gov/pubmed/36107978 http://dx.doi.org/10.1371/journal.pone.0274615 |