Identification of quantitative trait loci for survival in the mutant dynactin p150Glued mouse model of motor neuron disease

Amyotrophic lateral sclerosis (ALS) is the most common degenerative motor neuron disorder. Although most cases of ALS are sporadic, 5–10% of cases are familial, with mutations associated with over 40 genes. There is variation of ALS symptoms within families carrying the same mutation; the disease ma...

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Detalles Bibliográficos
Autores principales: Alexander, Guillermo M., Heiman-Patterson, Terry D., Bearoff, Frank, Sher, Roger B., Hennessy, Laura, Terek, Shannon, Caccavo, Nicole, Cox, Gregory A., Philip, Vivek M., Blankenhorn, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477371/
https://www.ncbi.nlm.nih.gov/pubmed/36107978
http://dx.doi.org/10.1371/journal.pone.0274615

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