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Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM
The Tetrahymena group I intron has been a key system in the understanding of RNA folding and misfolding. The molecule folds into a long-lived misfolded intermediate (M) in vitro, which has been known to form extensive native-like secondary and tertiary structures but is separated by an unknown kinet...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477386/ https://www.ncbi.nlm.nih.gov/pubmed/36067294 http://dx.doi.org/10.1073/pnas.2209146119 |