Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro

The protein mediator of ERBB2-driven cell motility 1 (Memo1) is connected to many signaling pathways that play key roles in cancer. Memo1 was recently postulated to bind copper (Cu) ions and thereby promote the generation of reactive oxygen species (ROS) in cancer cells. Since the concentration of C...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaolu, Walke, Gulshan R., Horvath, Istvan, Kumar, Ranjeet, Blockhuys, Stéphanie, Holgersson, Stellan, Walton, Paul H., Wittung-Stafshede, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477392/
https://www.ncbi.nlm.nih.gov/pubmed/36067318
http://dx.doi.org/10.1073/pnas.2206905119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477392/
https://www.ncbi.nlm.nih.gov/pubmed/36067318
http://dx.doi.org/10.1073/pnas.2206905119

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