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Repair of mismatched templates during Rad51-dependent Break-Induced Replication
Using budding yeast, we have studied Rad51-dependent break-induced replication (BIR), where the invading 3’ end of a site-specific double-strand break (DSB) and a donor template share 108 bp of homology that can be easily altered. BIR still occurs about 10% as often when every 6(th) base is mismatch...
Autores principales: | Choi, Jihyun, Kong, Muwen, Gallagher, Danielle N., Li, Kevin, Bronk, Gabriel, Cao, Yiting, Greene, Eric C., Haber, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477423/ https://www.ncbi.nlm.nih.gov/pubmed/36054210 http://dx.doi.org/10.1371/journal.pgen.1010056 |
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