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Flaxseed extract reduces tissue accumulation and enhances urinary excretion of chondroitin sulphate in the rat: a possible new path in substrate reduction therapy for mucopolysaccharidosis

CONTEXT: Chondroitin 6 sulphate (C6S) is a glycosaminoglycan (GAG) whose accumulation is notable in mucopolysaccharidosis type IVA and VII. Flaxseed, Linum usitatissimum L. (Linaceae) (FS), is reported to have comparable properties to those of soybean, a source of genistein, a potential new treatmen...

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Detalles Bibliográficos
Autores principales: Es-said, Sabir, Lafhal, Karima, Elkhiat, Abdelaati, Hammoud, Miloud, Regbaoui, Noureddine, Ezoubeiri, Aicha, Makbal, Rachida, Sbyea, Safia, Elhiba, Omar, Sellami, Souad, Rais, Hanane, Karim, Abdallah, Gamrani, Halima, Rada, Noureddine, Bouskraoui, Mohammed, Fdil, Naima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477488/
https://www.ncbi.nlm.nih.gov/pubmed/35634909
http://dx.doi.org/10.1080/13880209.2022.2068618