SECEDO: SNV-based subclone detection using ultra-low coverage single-cell DNA sequencing

MOTIVATION: Several recently developed single-cell DNA sequencing technologies enable whole-genome sequencing of thousands of cells. However, the ultra-low coverage of the sequenced data (<0.05× per cell) mostly limits their usage to the identification of copy number alterations in multi-megabase...

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Detalles Bibliográficos
Autores principales: Rozhoňová, Hana, Danciu, Daniel, Stark, Stefan, Rätsch, Gunnar, Kahles, André, Lehmann, Kjong-Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477524/
https://www.ncbi.nlm.nih.gov/pubmed/35900151
http://dx.doi.org/10.1093/bioinformatics/btac510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477524/
https://www.ncbi.nlm.nih.gov/pubmed/35900151
http://dx.doi.org/10.1093/bioinformatics/btac510

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