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SECEDO: SNV-based subclone detection using ultra-low coverage single-cell DNA sequencing
MOTIVATION: Several recently developed single-cell DNA sequencing technologies enable whole-genome sequencing of thousands of cells. However, the ultra-low coverage of the sequenced data (<0.05× per cell) mostly limits their usage to the identification of copy number alterations in multi-megabase...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477524/ https://www.ncbi.nlm.nih.gov/pubmed/35900151 http://dx.doi.org/10.1093/bioinformatics/btac510 |