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Identifying cellular cancer mechanisms through pathway-driven data integration
MOTIVATION: Cancer is a genetic disease in which accumulated mutations of driver genes induce a functional reorganization of the cell by reprogramming cellular pathways. Current approaches identify cancer pathways as those most internally perturbed by gene expression changes. However, driver genes c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477533/ https://www.ncbi.nlm.nih.gov/pubmed/35916710 http://dx.doi.org/10.1093/bioinformatics/btac493 |