Overexpressed Thrombospondin 2 Induced Osteogenic Differentiation of Valve Interstitial Cells via Inhibition of Akt/NF-κB Signaling Pathway to Promote Calcific Aortic Valve Disease Development

Thrombospondin 2 (THBS2) is reported to participate in the development of calcific aortic valve disease (CAVD), while the effects are not elucidated completely. The study aimed to explore the role and mechanism of THBS2 in CAVD. Differentially expressed genes related to stenosis and sclerosis were s...

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Detalles Bibliográficos
Autores principales: Yu, Cheng, Wu, Danna, Zhao, Chong, Wu, Chaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477632/
https://www.ncbi.nlm.nih.gov/pubmed/36118676
http://dx.doi.org/10.1155/2022/2022958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477632/
https://www.ncbi.nlm.nih.gov/pubmed/36118676
http://dx.doi.org/10.1155/2022/2022958

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