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Mechanism of AAA+ ATPase-mediated RuvAB–Holliday junction branch migration

The Holliday junction is a key intermediate formed during DNA recombination across all kingdoms of life(1). In bacteria, the Holliday junction is processed by two homo-hexameric AAA+ ATPase RuvB motors, which assemble together with the RuvA–Holliday junction complex to energize the strand-exchange r...

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Detalles Bibliográficos
Autores principales: Wald, Jiri, Fahrenkamp, Dirk, Goessweiner-Mohr, Nikolaus, Lugmayr, Wolfgang, Ciccarelli, Luciano, Vesper, Oliver, Marlovits, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477746/
https://www.ncbi.nlm.nih.gov/pubmed/36002576
http://dx.doi.org/10.1038/s41586-022-05121-1