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Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

Neurons born in the embryo can undergo a protracted period of maturation lasting well into postnatal life. How gene expression changes are regulated during maturation and whether they can be recapitulated in cultured neurons remains poorly understood. Here, we show that mouse motor neurons exhibit p...

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Detalles Bibliográficos
Autores principales: Patel, Tulsi, Hammelman, Jennifer, Aziz, Siaresh, Jang, Sumin, Closser, Michael, Michaels, Theodore L., Blum, Jacob A., Gifford, David K., Wichterle, Hynek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477853/
https://www.ncbi.nlm.nih.gov/pubmed/36109497
http://dx.doi.org/10.1038/s41467-022-33022-4