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Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage

AIMS/HYPOTHESIS: Enteroviral infection has been implicated consistently as a key environmental factor correlating with the appearance of autoimmunity and/or the presence of overt type 1 diabetes, in which pancreatic insulin-producing beta cells are destroyed by an autoimmune response. Genetic predis...

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Detalles Bibliográficos
Autores principales: Sioofy-Khojine, Amir-Babak, Richardson, Sarah J., Locke, Jonathan M., Oikarinen, Sami, Nurminen, Noora, Laine, Antti-Pekka, Downes, Kate, Lempainen, Johanna, Todd, John A., Veijola, Riitta, Ilonen, Jorma, Knip, Mikael, Morgan, Noel G., Hyöty, Heikki, Peakman, Mark, Eichmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477938/
https://www.ncbi.nlm.nih.gov/pubmed/35867130
http://dx.doi.org/10.1007/s00125-022-05753-y