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Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models

Large-scale genetic studies have revealed that the most prominent genes disrupted in autism are chromatin regulators mediating histone methylation/demethylation, suggesting the central role of epigenetic dysfunction in this disorder. Here, we show that histone lysine 4 dimethylation (H3K4me2), a his...

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Detalles Bibliográficos
Autores principales:	Rapanelli, Maximiliano, Williams, Jamal B., Ma, Kaijie, Yang, Fengwei, Zhong, Ping, Patel, Rajvi, Kumar, Manasa, Qin, Luye, Rein, Benjamin, Wang, Zi-Jun, Kassim, Bibi, Javidfar, Behnam, Couto, Lizette, Akbarian, Schahram, Yan, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477974/ https://www.ncbi.nlm.nih.gov/pubmed/35296809 http://dx.doi.org/10.1038/s41380-022-01508-8

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