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Tmsb10 triggers fetal Leydig differentiation by suppressing the RAS/ERK pathway
Leydig cells in fetal testes play crucial roles in masculinizing fetuses through androgen production. Gene knockout studies have revealed that growth factors are implicated in fetal Leydig cell (FLC) differentiation, but little is known about the mechanisms regulating this process. We investigate th...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478096/ https://www.ncbi.nlm.nih.gov/pubmed/36109592 http://dx.doi.org/10.1038/s42003-022-03941-5 |