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Tmsb10 triggers fetal Leydig differentiation by suppressing the RAS/ERK pathway

Leydig cells in fetal testes play crucial roles in masculinizing fetuses through androgen production. Gene knockout studies have revealed that growth factors are implicated in fetal Leydig cell (FLC) differentiation, but little is known about the mechanisms regulating this process. We investigate th...

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Detalles Bibliográficos
Autores principales: Inoue, Miki, Baba, Takashi, Takahashi, Fumiya, Terao, Miho, Yanai, Shogo, Shima, Yuichi, Saito, Daisuke, Sugihara, Kei, Miura, Takashi, Takada, Shuji, Suyama, Mikita, Ohkawa, Yasuyuki, Morohashi, Ken-ichirou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478096/
https://www.ncbi.nlm.nih.gov/pubmed/36109592
http://dx.doi.org/10.1038/s42003-022-03941-5