Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice

Community acquired pneumonia, mainly caused by Streptococcus pneumoniae (S.pn.), is a common cause of death worldwide. Despite adequate antibiotic therapy, pneumococcal pneumonia can induce pulmonary endothelial hyperpermeability leading to acute lung injury, which often requires mechanical ventilat...

Descripción completa

Detalles Bibliográficos
Autores principales: Lask, Aina, Gutbier, Birgitt, Kershaw, Olivia, Nouailles, Geraldine, Gruber, Achim D., Müller-Redetzky, Holger C., Chackowicz, Steven, Hamilton, Douglas A., Van Slyke, Paul, Witzenrath, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478100/
https://www.ncbi.nlm.nih.gov/pubmed/36109537
http://dx.doi.org/10.1038/s41598-022-19560-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478100/
https://www.ncbi.nlm.nih.gov/pubmed/36109537
http://dx.doi.org/10.1038/s41598-022-19560-3

Ejemplares similares