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Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice
Community acquired pneumonia, mainly caused by Streptococcus pneumoniae (S.pn.), is a common cause of death worldwide. Despite adequate antibiotic therapy, pneumococcal pneumonia can induce pulmonary endothelial hyperpermeability leading to acute lung injury, which often requires mechanical ventilat...
Autores principales: | Lask, Aina, Gutbier, Birgitt, Kershaw, Olivia, Nouailles, Geraldine, Gruber, Achim D., Müller-Redetzky, Holger C., Chackowicz, Steven, Hamilton, Douglas A., Van Slyke, Paul, Witzenrath, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478100/ https://www.ncbi.nlm.nih.gov/pubmed/36109537 http://dx.doi.org/10.1038/s41598-022-19560-3 |
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