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PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells

In breast cancer, Poly(ADP-ribose) polymerase 3 (PARP3) has been identified as a key driver of tumor aggressiveness exemplifying its selective inhibition as a promising surrogate for clinical activity onto difficult-to-treat cancers. Here we explored the role of PARP3 in the oncogenicity of glioblas...

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Detalles Bibliográficos
Autores principales: Nguekeu-Zebaze, Leonel, Hanini, Najat, Noll, Aurélia, Wadier, Nadège, Amé, Jean-Christophe, Roegel, Lisa, Dantzer, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478127/
https://www.ncbi.nlm.nih.gov/pubmed/36109561
http://dx.doi.org/10.1038/s41598-022-19525-6