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Disarming of type I-F CRISPR-Cas surveillance complex by anti-CRISPR proteins AcrIF6 and AcrIF9

CRISPR-Cas systems are prokaryotic adaptive immune systems that protect against phages and other invading nucleic acids. The evolutionary arms race between prokaryotes and phages gave rise to phage anti-CRISPR (Acr) proteins that act as a counter defence against CRISPR-Cas systems by inhibiting the...

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Detalles Bibliográficos
Autores principales: Kupcinskaite, Egle, Tutkus, Marijonas, Kopūstas, Aurimas, Ašmontas, Simonas, Jankunec, Marija, Zaremba, Mindaugas, Tamulaitiene, Giedre, Sinkunas, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478129/
https://www.ncbi.nlm.nih.gov/pubmed/36109551
http://dx.doi.org/10.1038/s41598-022-19797-y