Cargando…

Disarming of type I-F CRISPR-Cas surveillance complex by anti-CRISPR proteins AcrIF6 and AcrIF9

CRISPR-Cas systems are prokaryotic adaptive immune systems that protect against phages and other invading nucleic acids. The evolutionary arms race between prokaryotes and phages gave rise to phage anti-CRISPR (Acr) proteins that act as a counter defence against CRISPR-Cas systems by inhibiting the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kupcinskaite, Egle, Tutkus, Marijonas, Kopūstas, Aurimas, Ašmontas, Simonas, Jankunec, Marija, Zaremba, Mindaugas, Tamulaitiene, Giedre, Sinkunas, Tomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478129/ https://www.ncbi.nlm.nih.gov/pubmed/36109551 http://dx.doi.org/10.1038/s41598-022-19797-y

Ejemplares similares

Structural basis for inhibition of the type I-F CRISPR–Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14
por: Gabel, Clinton, et al.
Publicado: (2020)

Structural and mechanistic insights into the CRISPR inhibition of AcrIF7
por: Kim, Iktae, et al.
Publicado: (2020)

Distribution and molecular evolution of the anti-CRISPR family AcrIF7
por: Figueroa, Wendy, et al.
Publicado: (2023)

Mechanistic insights into the inhibition of the CRISPR-Cas surveillance complex by anti-CRISPR protein AcrIF13
por: Wang, Hao, et al.
Publicado: (2022)

Anti-CRISPR AcrIF9 functions by inducing the CRISPR–Cas complex to bind DNA non-specifically
por: Lu, Wang-Ting, et al.
Publicado: (2021)

Molecular basis of dual anti-CRISPR and auto-regulatory functions of AcrIF24
por: Kim, Gi Eob, et al.
Publicado: (2022)

Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24
por: Yang, Lingguang, et al.
Publicado: (2022)

Structural and mechanistic insights into the inhibition of type I-F CRISPR-Cas system by anti-CRISPR protein AcrIF23
por: Ren, Junhui, et al.
Publicado: (2022)

Insights into the dual functions of AcrIF14 during the inhibition of type I-F CRISPR–Cas surveillance complex
por: Liu, Xi, et al.
Publicado: (2021)

AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex
por: Hirschi, Marscha, et al.
Publicado: (2020)

A high‐resolution (1.2 Å) crystal structure of the anti‐CRISPR protein AcrIF9
por: Kim, Gi Eob, et al.
Publicado: (2020)

Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage
por: Gao, Zhengyu, et al.
Publicado: (2022)

Inhibition mechanisms of CRISPR-Cas9 by AcrIIA17 and AcrIIA18
por: Wang, Xiaoshen, et al.
Publicado: (2021)

smFRET Detection of Cis and Trans DNA Interactions by the BfiI Restriction Endonuclease
por: Ivanovaitė, Šaru̅nė, et al.
Publicado: (2023)

Inhibitory mechanism of CRISPR-Cas9 by AcrIIC4
por: Li, Xuzichao, et al.
Publicado: (2023)

The miEye: Bench-top super-resolution microscope with cost-effective equipment
por: Alsamsam, Mohammad Nour, et al.
Publicado: (2022)

Oriented Soft DNA Curtains for Single-Molecule Imaging
por: Kopu̅stas, Aurimas, et al.
Publicado: (2021)

Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
por: Thavalingam, Annoj, et al.
Publicado: (2019)

DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system
por: Tuminauskaite, Donata, et al.
Publicado: (2020)

Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR–Cas complex revealed by cryo-EM
por: Zhang, Kaiming, et al.
Publicado: (2020)

Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins
por: Lee, Jooyoung, et al.
Publicado: (2018)

The structure of AcrIC9 revealing the putative inhibitory mechanism of AcrIC9 against the type IC CRISPR–Cas system
por: Kang, Yong Jun, et al.
Publicado: (2023)

AcrNET: predicting anti-CRISPR with deep learning
por: Li, Yunxiang, et al.
Publicado: (2023)

Solution structure and dynamics of anti-CRISPR AcrIIA4, the Cas9 inhibitor
por: Kim, Iktae, et al.
Publicado: (2018)

Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a
por: Knott, Gavin J, et al.
Publicado: (2019)

Intrinsic disorder is essential for Cas9 inhibition of anti-CRISPR AcrIIA5
por: An, So Young, et al.
Publicado: (2020)

Gene drive inhibition by the anti-CRISPR proteins AcrIIA2 and AcrIIA4 in Saccharomyces cerevisiae
por: Basgall, Erianna M., et al.
Publicado: (2018)

Crystal structure of an anti-CRISPR protein, AcrIIA1
por: Ka, Donghyun, et al.
Publicado: (2018)

Corrigendum: Gene drive inhibition by the anti-CRISPR proteins AcrIIA2 and AcrIIA4 in Saccharomyces cerevisiae
por: Basgall, Erianna M., et al.
Publicado: (2018)

AcrFinder: genome mining anti-CRISPR operons in prokaryotes and their viruses
por: Yi, Haidong, et al.
Publicado: (2020)

AcrDB: a database of anti-CRISPR operons in prokaryotes and viruses
por: Huang, Le, et al.
Publicado: (2020)

Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing
por: Garcia, Bianca, et al.
Publicado: (2019)

Characterization of the AcrIIC1 anti‒CRISPR protein for Cas9‒based genome engineering in E. coli
por: Trasanidou, Despoina, et al.
Publicado: (2023)

AcrHub: an integrative hub for investigating, predicting and mapping anti-CRISPR proteins
por: Wang, Jiawei, et al.
Publicado: (2020)

PreAcrs: a machine learning framework for identifying anti-CRISPR proteins
por: Zhu, Lin, et al.
Publicado: (2022)

CRISPR-Cas12a nucleases function with structurally engineered crRNAs: SynThetic trAcrRNA
por: Jedrzejczyk, D. J., et al.
Publicado: (2022)

A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1
por: Zhao, Yanan, et al.
Publicado: (2022)

The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
por: Forsberg, Kevin J., et al.
Publicado: (2021)

High-MOI induces rapid CRISPR spacer acquisition in Sulfolobus from an acr deficient virus
por: Bhoobalan-Chitty, Yuvaraj, et al.
Publicado: (2022)

Expression of acrA and acrB Genes in Esherichia coli Mutants with or without marR or acrR Mutations
por: Pourahmad Jaktaji, Razieh, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_svdtu524l522vn9596ojvnkqm8