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Interphotoreceptor matrix proteoglycans IMPG1 and IMPG2 proteolyze in the SEA domain and reveal localization mutual dependency

The interphotoreceptor matrix (IPM) is a specialized extracellular mesh of molecules surrounding the inner and outer segments of photoreceptor neurons. Interphotoreceptor matrix proteoglycan 1 and 2 (IMPG1 and IMPG2) are major components of the IPM. Both proteoglycans possess SEA (sperm protein, ent...

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Detalles Bibliográficos
Autores principales: Mitchell, Benjamin, Coulter, Chloe, Geldenhuys, Werner J., Rhodes, Scott, Salido, Ezequiel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478142/
https://www.ncbi.nlm.nih.gov/pubmed/36109576
http://dx.doi.org/10.1038/s41598-022-19910-1