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Colivelin, a synthetic derivative of humanin, ameliorates endothelial injury and glycocalyx shedding after sepsis in mice

Endothelial dysfunction plays a central role in the pathogenesis of sepsis-mediated multiple organ failure. Several clinical and experimental studies have suggested that the glycocalyx is an early target of endothelial injury during an infection. Colivelin, a synthetic derivative of the mitochondria...

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Detalles Bibliográficos
Autores principales: Urban, Catherine, Hayes, Hannah V., Piraino, Giovanna, Wolfe, Vivian, Lahni, Patrick, O’Connor, Michael, Phares, Ciara, Zingarelli, Basilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478210/
https://www.ncbi.nlm.nih.gov/pubmed/36119052
http://dx.doi.org/10.3389/fimmu.2022.984298