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Colivelin, a synthetic derivative of humanin, ameliorates endothelial injury and glycocalyx shedding after sepsis in mice
Endothelial dysfunction plays a central role in the pathogenesis of sepsis-mediated multiple organ failure. Several clinical and experimental studies have suggested that the glycocalyx is an early target of endothelial injury during an infection. Colivelin, a synthetic derivative of the mitochondria...
Autores principales: | Urban, Catherine, Hayes, Hannah V., Piraino, Giovanna, Wolfe, Vivian, Lahni, Patrick, O’Connor, Michael, Phares, Ciara, Zingarelli, Basilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478210/ https://www.ncbi.nlm.nih.gov/pubmed/36119052 http://dx.doi.org/10.3389/fimmu.2022.984298 |
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