Effects of dose change on the success of clinical trials

The search for disease modifying therapies in Alzheimers disease (AD) has recently led to promising results but also revealed design issues in clinical trials themselves. Of particular importance is the potential statistical challenges that can arise when dosages change after an interim analysis, wh...

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Detalles Bibliográficos
Autores principales: Shan, Guogen, Ritter, Aaron, Miller, Justin, Bernick, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478360/
https://www.ncbi.nlm.nih.gov/pubmed/36117568
http://dx.doi.org/10.1016/j.conctc.2022.100988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478360/
https://www.ncbi.nlm.nih.gov/pubmed/36117568
http://dx.doi.org/10.1016/j.conctc.2022.100988

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