The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways

Ov-ASP-1 (rASP-1), a parasite-derived protein secreted by the helminth Onchocerca volvulus, is an adjuvant which enhances the potency of the influenza trivalent vaccine (IIV3), even when used with 40-fold less IIV3. This study is aimed to provide a deeper insight into the molecular networks that und...

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Detalles Bibliográficos
Autores principales: George, Parakkal Jovvian, Marches, Radu, Nehar-Belaid, Djamel, Banchereau, Jacques, Lustigman, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478378/
https://www.ncbi.nlm.nih.gov/pubmed/36119026
http://dx.doi.org/10.3389/fimmu.2022.961094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478378/
https://www.ncbi.nlm.nih.gov/pubmed/36119026
http://dx.doi.org/10.3389/fimmu.2022.961094

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