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Impaired myocellular Ca(2+) cycling in protein phosphatase PP2A-B56α KO mice is normalized by β-adrenergic stimulation

The activity of protein phosphatase 2A (PP2A) is determined by the expression and localization of the regulatory B-subunits. PP2A-B56α is the dominant isoform of the B′-family in the heart. Its role in regulating the cardiac response to β-adrenergic stimulation is not yet fully understood. We theref...

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Detalles Bibliográficos
Autores principales: Glaser, Dennis, Heinick, Alexander, Herting, Julius R., Massing, Fabian, Müller, Frank U., Pauls, Paul, Rozhdestvensky, Timofey S., Schulte, Jan S., Seidl, Matthias D., Skryabin, Boris V., Stümpel, Frank, Kirchhefer, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478386/
https://www.ncbi.nlm.nih.gov/pubmed/35963431
http://dx.doi.org/10.1016/j.jbc.2022.102362