Cargando…

Impaired myocellular Ca(2+) cycling in protein phosphatase PP2A-B56α KO mice is normalized by β-adrenergic stimulation

The activity of protein phosphatase 2A (PP2A) is determined by the expression and localization of the regulatory B-subunits. PP2A-B56α is the dominant isoform of the B′-family in the heart. Its role in regulating the cardiac response to β-adrenergic stimulation is not yet fully understood. We theref...

Descripción completa

Detalles Bibliográficos
Autores principales:	Glaser, Dennis, Heinick, Alexander, Herting, Julius R., Massing, Fabian, Müller, Frank U., Pauls, Paul, Rozhdestvensky, Timofey S., Schulte, Jan S., Seidl, Matthias D., Skryabin, Boris V., Stümpel, Frank, Kirchhefer, Uwe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478386/ https://www.ncbi.nlm.nih.gov/pubmed/35963431 http://dx.doi.org/10.1016/j.jbc.2022.102362

Ejemplares similares

Hypercontractile cardiac phenotype in mice overexpressing the regulatory subunit PR72 of protein phosphatase 2A
por: Herting, Julius R., et al.
Publicado: (2023)

Role of type 2A phosphatase regulatory subunit B56α in regulating cardiac responses to β-adrenergic stimulation in vivo
por: Puhl, Sarah-Lena, et al.
Publicado: (2019)

Myocellular characteristics in rheumatoid arthritis and osteoarthritis patients
por: Mueller, Sandro Manuel, et al.
Publicado: (2018)

BC1 RNA motifs required for dendritic transport in vivo
por: Robeck, Thomas, et al.
Publicado: (2016)

Changes in metabolism but not myocellular signaling by training with CHO‐restriction in endurance athletes
por: Gejl, Kasper D., et al.
Publicado: (2018)

Homozygous CREM-IbΔC-X Overexpressing Mice Are a Reliable and Effective Disease Model for Atrial Fibrillation
por: Stümpel, Frank T., et al.
Publicado: (2018)

Resveratrol‐induced remodelling of myocellular lipid stores: A study in metabolically compromised humans
por: van Polanen, Nynke, et al.
Publicado: (2021)

β-Adrenergic regulation of cardiac type 2A protein phosphatase through phosphorylation of regulatory subunit B56δ at S573
por: Ranieri, Antonella, et al.
Publicado: (2018)

Reference Genes across Nine Brain Areas of Wild Type and Prader-Willi Syndrome Mice: Assessing Differences in Igfbp7, Pcsk1, Nhlh2 and Nlgn3 Expression
por: Kummerfeld, Delf-Magnus, et al.
Publicado: (2022)

Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation
por: Zhang, Shaoping, et al.
Publicado: (2014)

ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity
por: Sparks, Lauren M., et al.
Publicado: (2016)

Circular RNA Encoded Amyloid Beta peptides—A Novel Putative Player in Alzheimer’s Disease
por: Mo, Dingding, et al.
Publicado: (2020)

A Comprehensive Review of Genetically Engineered Mouse Models for Prader-Willi Syndrome Research
por: Kummerfeld, Delf-Magnus, et al.
Publicado: (2021)

Piroxicam fails to reduce myocellular enzyme leakage and delayed onset muscle soreness induced by isokinetic eccentric exercise
por: Croisier, J-L., et al.
Publicado: (1996)

Differential effects of saturated versus unsaturated dietary fatty acids on weight gain and myocellular lipid profiles in mice
por: Timmers, S, et al.
Publicado: (2011)

Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review
por: de Queiros, Victor Sabino, et al.
Publicado: (2022)

DNA barcoding reveals that injected transgenes are predominantly processed by homologous recombination in mouse zygote
por: Smirnov, Alexander, et al.
Publicado: (2020)

Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase
por: Foley, Emily A., et al.
Publicado: (2011)

Polycystin-1 Inhibits Cell Proliferation through Phosphatase PP2A/B56α
por: Tang, Yan, et al.
Publicado: (2019)

Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting
por: Cole, Calvin L., et al.
Publicado: (2021)

A universal approach to investigate circRNA protein coding function
por: Mo, Dingding, et al.
Publicado: (2019)

A simple method for in-house Pfu DNA polymerase purification for high-fidelity PCR amplification
por: Sankar, Prabu Siva, et al.
Publicado: (2019)

Deletion of the MBII-85 snoRNA Gene Cluster in Mice Results in Postnatal Growth Retardation
por: Skryabin, Boris V, et al.
Publicado: (2007)

Two primate-specific small non-protein-coding RNAs in transgenic mice: neuronal expression, subcellular localization and binding partners
por: Khanam, Tasneem, et al.
Publicado: (2007)

Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity
por: Meex, Ruth C.R., et al.
Publicado: (2010)

Label-free CARS microscopy reveals similar triacylglycerol acyl chain length and saturation in myocellular lipid droplets of athletes and individuals with type 2 diabetes
por: Daemen, Sabine, et al.
Publicado: (2020)

Maternal transcription of non-protein coding RNAs from the PWS-critical region rescues growth retardation in mice
por: Rozhdestvensky, Timofey S., et al.
Publicado: (2016)

Las 56 Africas : guía política
por: Tenaille, Frank
Publicado: (1997)

Spatial learning and long‐term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice
por: Manyes, Lara, et al.
Publicado: (2018)

Time origin and structural analysis of the induced CRISPR/cas9 megabase-sized deletions and duplications involving the Cntn6 gene in mice
por: Pristyazhnyuk, Inna E., et al.
Publicado: (2019)

Antibody response against koala retrovirus (KoRV) in koalas harboring KoRV-A in the presence or absence of KoRV-B
por: Olagoke, O., et al.
Publicado: (2019)

Vimentin dephosphorylation at ser-56 is regulated by type 1 protein phosphatase in smooth muscle
por: Li, Jia, et al.
Publicado: (2016)

Ectopic expression of Snord115 in choroid plexus interferes with editing but not splicing of 5-Ht2c receptor pre-mRNA in mice
por: Raabe, Carsten A., et al.
Publicado: (2019)

Organ Correlation with Tryptophan Metabolism Obtained by Analyses of TDO-KO and QPRT-KO Mice
por: Shibata, Katsumi, et al.
Publicado: (2016)

Phenotyping of Mice with Heart Specific Overexpression of A(2A)-Adenosine Receptors: Evidence for Cardioprotective Effects of A(2A)-Adenosine Receptors
por: Boknik, Peter, et al.
Publicado: (2018)

The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model
por: Janghorban, Mahnaz, et al.
Publicado: (2017)

Initial Characterization of Stressed Transgenic Mice With Cardiomyocyte-Specific Overexpression of Protein Phosphatase 2C
por: Bollmann, Paula, et al.
Publicado: (2021)

Decay of tau-leptons into Ko_s
por: Frey, A
Publicado: (1992)

First person – Masayoshi Ko
Publicado: (2021)

First person – Hungtang Ko
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mb8tjnhhep1mst5gvcjg992bq5