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Placental growth factor stabilizes VEGF receptor-2 protein in retinal pigment epithelial cells by downregulating glycogen synthase kinase 3 activity

Placental growth factor (PlGF) belongs to the vascular endothelial growth factor (VEGF) family of proteins that participate in angiogenesis and vasculogenesis. Anti-VEGF therapy has become the standard treatment for ocular angiogenic disorders in ophthalmological practice. However, there is emerging...

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Detalles Bibliográficos
Autores principales: Murata, Miyuki, Noda, Kousuke, Kase, Satoru, Hase, Keitaro, Wu, Di, Ando, Ryo, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478399/
https://www.ncbi.nlm.nih.gov/pubmed/35970387
http://dx.doi.org/10.1016/j.jbc.2022.102378