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HLA‐A*24:02 increase the risk of allopurinol‐induced drug reaction with eosinophilia and systemic symptoms in HLA‐B*58:01 carriers in a Korean population; a multicenter cross‐sectional case‐control study

BACKGROUND: HLA‐B*58:01 is a well‐known risk factor for allopurinol‐induced severe cutaneous adverse reactions (SCARs). However, only a minority of HLA‐B*58:01 carriers suffer SCARs after taking allopurinol. The aim of this study was to investigate subsidiary genetic markers that could identify thos...

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Detalles Bibliográficos
Autores principales: Kim, Mi‐Yeong, Yun, James, Kang, Dong‐Yoon, Kim, Tae Hee, Oh, Min‐Kyung, Lee, Sunggun, Kang, Min‐Gyu, Nam, Young‐Hee, Choi, Jeong‐Hee, Yang, Min‐Suk, Han, Seung Seok, Lee, Hajeong, Cho, Hyun‐Jai, Yang, Jaeseok, Oh, Kook‐Hwan, Kim, Yon Su, Jung, Jae Woo, Lee, Kye Hwa, Kang, Hye‐Ryun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478421/
https://www.ncbi.nlm.nih.gov/pubmed/36176736
http://dx.doi.org/10.1002/clt2.12193