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HLA‐A*24:02 increase the risk of allopurinol‐induced drug reaction with eosinophilia and systemic symptoms in HLA‐B*58:01 carriers in a Korean population; a multicenter cross‐sectional case‐control study
BACKGROUND: HLA‐B*58:01 is a well‐known risk factor for allopurinol‐induced severe cutaneous adverse reactions (SCARs). However, only a minority of HLA‐B*58:01 carriers suffer SCARs after taking allopurinol. The aim of this study was to investigate subsidiary genetic markers that could identify thos...
Autores principales: | Kim, Mi‐Yeong, Yun, James, Kang, Dong‐Yoon, Kim, Tae Hee, Oh, Min‐Kyung, Lee, Sunggun, Kang, Min‐Gyu, Nam, Young‐Hee, Choi, Jeong‐Hee, Yang, Min‐Suk, Han, Seung Seok, Lee, Hajeong, Cho, Hyun‐Jai, Yang, Jaeseok, Oh, Kook‐Hwan, Kim, Yon Su, Jung, Jae Woo, Lee, Kye Hwa, Kang, Hye‐Ryun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478421/ https://www.ncbi.nlm.nih.gov/pubmed/36176736 http://dx.doi.org/10.1002/clt2.12193 |
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