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Genetic disruption of the Gipr in Apoe(−/−) mice promotes atherosclerosis

OBJECTIVE: The gut hormone glucose-dependent insulinotropic polypeptide (GIP) stimulates beta cell function and improves glycemia through its incretin actions. GIP also regulates endothelial function and suppresses adipose tissue inflammation through control of macrophage activity. Activation of the...

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Detalles Bibliográficos
Autores principales: Pujadas, Gemma, Baggio, Laurie L., Kaur, Kiran Deep, McLean, Brent A., Cao, Xiemin, Drucker, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478451/
https://www.ncbi.nlm.nih.gov/pubmed/36055579
http://dx.doi.org/10.1016/j.molmet.2022.101586