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Genetic disruption of the Gipr in Apoe(−/−) mice promotes atherosclerosis
OBJECTIVE: The gut hormone glucose-dependent insulinotropic polypeptide (GIP) stimulates beta cell function and improves glycemia through its incretin actions. GIP also regulates endothelial function and suppresses adipose tissue inflammation through control of macrophage activity. Activation of the...
Autores principales: | Pujadas, Gemma, Baggio, Laurie L., Kaur, Kiran Deep, McLean, Brent A., Cao, Xiemin, Drucker, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478451/ https://www.ncbi.nlm.nih.gov/pubmed/36055579 http://dx.doi.org/10.1016/j.molmet.2022.101586 |
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