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PACAP attenuates hepatic lipid accumulation through the FAIM/AMPK/IRβ axis during overnutrition

OBJECTIVE: Pituitary adenylate cyclase-activating polypeptide (PACAP) was reported to attenuate hepatic lipid accumulation in overnutrition-related metabolic disorder, mediated by up-regulation of fas apoptosis inhibitory molecule (FAIM). However, how PACAP regulates FAIM in metabolic tissues remain...

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Detalles Bibliográficos
Autores principales: Luo, Wei, Dai, Jiaxin, Liu, Jianmin, Huang, Yongmei, Zheng, Ziqiong, Xu, Pei, Ma, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478455/
https://www.ncbi.nlm.nih.gov/pubmed/36055580
http://dx.doi.org/10.1016/j.molmet.2022.101584