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Advantages of CRISPR-Cas9 combined organoid model in the study of congenital nervous system malformations
In the past 10 years, gene-editing and organoid culture have completely changed the process of biology. Congenital nervous system malformations are difficult to study due to their polygenic pathogenicity, the complexity of cellular and neural regions of the brain, and the dysregulation of specific n...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478582/ https://www.ncbi.nlm.nih.gov/pubmed/36118578 http://dx.doi.org/10.3389/fbioe.2022.932936 |