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The changing view of insulin granule mobility: From conveyor belt to signaling hub

Before the advent of TIRF microscopy the fate of the insulin granule prior to secretion was deduced from biochemical investigations, electron microscopy and electrophysiological measurements. Since Calcium-triggered granule fusion is indisputably necessary to release insulin into the extracellular s...

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Detalles Bibliográficos
Autores principales: Gaus, Bastian, Brüning, Dennis, Groß, Sofie, Müller, Michael, Rustenbeck, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478610/
https://www.ncbi.nlm.nih.gov/pubmed/36120467
http://dx.doi.org/10.3389/fendo.2022.983152